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Search Results for " matrix metalloproteinase-12 "

Targets Recommended: MMP

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T12414	PF-00356231 hydrochloride	MMP	Proteases/Proteasome
	PF-00356231 hydrochloride 是基质金属蛋白酶 MMP-12 的抑制剂，IC50 为 1.4 μM。
T83168	Aderamastat FP-003,FP-025	MMP	Proteases/Proteasome
	Aderamastat (FP-025) 是一种具有口服活性的基质金属蛋白酶12（MMP-12）抑制剂，适用于过敏性哮喘、COPD与肺纤维化的研究。
T14322	ARP-100 MMP-2 Inhibitor III	MMP	Proteases/Proteasome
	ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM)，MMP-3 (4.5 μM)，MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1＇口袋相互作用，并在体外对基质胶的侵袭模型中显示抗侵袭特性。

化合物

PF-00356231 hydrochloride

Cat.No: T12414

Target: MMP

Cat.No: T83168

Synonym: FP-003,FP-025

Target: MMP

Cat.No: T14322

Synonym: MMP-2 Inhibitor III

Target: MMP

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00942	MMP-12 Protein, Mouse, Recombinant (His) Mme,Mmp12,MMP-12,Mmel,Matrix ...	Mouse	HEK293 Cells
	Matrix metalloproteinase-12（MMP12） is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain) HME,ME,MMP-12,MME,matrix metallopeptidase ...	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-02642	UBE2W Protein, Human, Recombinant (His) UBC16,UBC-16,ubiquitin-conjugating enzyme E2W (putative)	Human	E. coli
	Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of protein ubiquitination. The modification of protein with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2W is a member of th...
TMPY-04620	Neurofascin Protein, Human, Recombinant (hFc) neurofascin,NRCAML,NF	Human	HEK293 Cells
	Neurofascin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 130 kDa and the accession number is O94856-12.
TMPY-00031	Neuregulin-1/NRG1 Protein, Human, Recombinant (His) HRG1,GGF2,HRG,NDF,MSTP131,HRGA,GGF,neuregulin 1,HGL,SMDF,ARI...	Human	HEK293 Cells
	Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
TMPY-00479	Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) ARIA,neuregulin 1,GGF2,MSTP131,GGF,MST131,HGL,NDF,SMDF,HRG1,...	Human	HEK293 Cells
	Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.
TMPY-03797	Neurofascin Protein, Human, Recombinant (His) neurofascin,NF,NRCAML	Human	HEK293 Cells
	Neurofascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.4 kDa and the accession number is O94856-12.

重组蛋白

MMP-12 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00942

Species: Mouse

Expression System: HEK293 Cells

MMP-12 Protein, Human, Recombinant (catalytic domain)

Cat.No: TMPY-02869

Species: Human

Expression System: E. coli

UBE2W Protein, Human, Recombinant (His)

Cat.No: TMPY-02642

Species: Human

Expression System: E. coli

Neurofascin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04620

Species: Human

Expression System: HEK293 Cells

Neuregulin-1/NRG1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00031

Species: Human

Expression System: HEK293 Cells

Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00479

Species: Human

Expression System: HEK293 Cells

Neurofascin Protein, Human, Recombinant (His)

Cat.No: TMPY-03797

Species: Human

Expression System: HEK293 Cells

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